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1

Simulation-based medical education in clinical skills laboratory

Akaike, Masashi, Fukutomi, Miki, Nagamune, Masami, Fujimoto, Akiko, Tsuji, Akiko, Ishida, Kazuko, Iwata, Takashi

Journal:

The Journal of Medical Investigation

Year:

2012

Language:

english

File:

PDF, 435 KB

english, 2012

2

Localization and amount of myoglobin and myoglobin mRNA in ragged-red fiber of patients with mitochondrial encephalomyopathy

Makoto Kunishige, Takao Mitsui, Masashi Akaike, Masayuki Shono, Hisaomi Kawai, Shiro Saito

Journal:

Year:

1996

Language:

english

File:

PDF, 890 KB

english, 1996

3

Clinical, pathological, and genetic features of limb-girdle muscular dystrophy type 2A with new calpain 3 gene mutations in seven patients from three Japanese families

Hisaomi Kawai, Masashi Akaike, Makoto Kunishige, Toshio Inui, Katsuhito Adachi, Chiyomi Kimura, Masakazu Kawajiri, Yoshihiko Nishida, Itsuro Endo, Setsuko Kashiwagi, Hiroshi Nishino, Tsutomu Fujiwara,

Journal:

Year:

1998

Language:

english

File:

PDF, 469 KB

english, 1998

4

Overexpressions of myoglobin and antioxidant enzymes in ragged-red fibers of skeletal muscle from patients with mitochondrial encephalomyopathy

Makoto Kunishige, Takao Mitsui, Masashi Akaike, Masakazu Kawajiri, Masayuki Shono, Hisaomi Kawai, Toshio Matsumoto

Journal:

Year:

2003

Language:

english

File:

PDF, 827 KB

english, 2003

5

Mitochondrial encephalomyopathy with autosomal dominant inheritance: A clinical and genetic entity of mitochondrial diseases

Hisaomi Kawai, Masashi Akaike, Kenji Yokoi, Yoshihiko Nishida, Makoto Kunishige, Hideki Mine, Shiro Saito

Journal:

Year:

1995

Language:

english

File:

PDF, 680 KB

english, 1995

6

View of physicians on and barriers to patient enrollment in a multicenter clinical trial: experience in a Japanese rural area

Hiroaki Yanagawa, Masatoshi Kishuku, Masashi Akaike, Hiroyuki Azuma, Minoru Irahara

Journal:

International Archives of Medicine

Year:

2010

Language:

english

File:

PDF, 428 KB

english, 2010

7

Transforming Growth Factor- β 1 as a Common Target Molecule for Development of Cardiovascular Diseases, Renal Insufficiency and Metabolic Syndrome

Aihara, Ken-ichi, Ikeda, Yasumasa, Yagi, Shusuke, Akaike, Masashi, Matsumoto, Toshio

Journal:

Cardiology Research and Practice

Year:

2011

Language:

english

File:

PDF, 1.46 MB

english, 2011

8

Functional association between nicotinic acetylcholine receptor and sarcomeric proteins via actin and desmin filaments

Takao Mitsui, Masakazu Kawajiri, Makoto Kunishige, Takenori Endo, Masashi Akaike, Kenji Aki, Toshio Matsumoto

Journal:

Journal of Cellular Biochemistry

Year:

2000

Language:

english

File:

PDF, 367 KB

english, 2000

9

Balloon diameter of the inoue balloon catheter during percutaneous transvenous mitral commissurotomy: Clinical and experimental study

Seiki Nagata, Fuminobu Ishikura, Takashi Yamabe, Masashi Akaike, Kohji Kimura, Kunio Miyatake

Journal:

Catheterization and Cardiovascular Interventions

Year:

1991

Language:

english

File:

PDF, 484 KB

english, 1991

10

Presence of human T-lymphotropic virus type II-related genes in DNA of peripheral leukocytes from patients with autoimmune thyroid diseases

Kenji Yokoi, Hisaomi Kawai, Masashi Akaike, Hideki Mine, Shiro Saito

Journal:

Journal of Medical Virology

Year:

1995

Language:

english

File:

PDF, 697 KB

english, 1995

11

Successful Combination Therapy—Flunarizine, Pentoxifylline, and Cholestyramine— for Spur Cell Anemia

Ken-ichi Aihara, Hiroyuki Azuma, Yasumasa Ikeda, Masashi Akaike, Masahiro Abe, Takashi Sugihara, Toshio Matsumoto

Journal:

International Journal of Hematology

Year:

2001

Language:

english

File:

PDF, 98 KB

english, 2001

12

Mitochondrial damage in patients with long-term corticosteroid therapy: development of oculoskeletal symptoms similar to mitochondrial disease

Takao Mitsui, Yoshifumi Umaki, Masakazu Nagasawa, Masashi Akaike, Kenji Aki, Hiroyuki Azuma, Shyuji Ozaki, Masaaki Odomi, Toshio Matsumoto

Journal:

Acta Neuropathologica

Year:

2002

Language:

english

File:

PDF, 244 KB

english, 2002

13

Apoptosis-related changes in skeletal muscles of patients with mitochondrial diseases

Yoshifumi Umaki, Takao Mitsui, Itsuro Endo, Masashi Akaike, Toshio Matsumoto

Journal:

Acta Neuropathologica

Year:

2002

Language:

english

File:

PDF, 377 KB

english, 2002

14

Chronic corticosteroid administration causes mitochondrial dysfunction in skeletal muscle

Takao Mitsui, Hiroyuki Azuma, Masakazu Nagasawa, Takahiko Iuchi, Masashi Akaike, Masaaki Odomi, Toshio Matsumoto

Journal:

Journal of Neurology

Year:

2002

Language:

english

File:

PDF, 639 KB

english, 2002

15

Protective effects of ifenprodil against glutamate-induced neurotoxicity in cultured retinal neurons

Shen Zhang, S. Kashii, Hiroki Yasuyoshi, Masashi Kikuchi, Yoshihito Honda, Katsuyuki Kaneda, Sati Sato, Akinori Akaike

Journal:

Graefe's Archive for Clinical and Experimental Ophthalmology

Year:

2000

Language:

english

File:

PDF, 155 KB

english, 2000

16

Platypnea-Orthodeoxia Syndrome Associated with Patent Foramen Ovale and Aortic Ectasia : CME

Kenya Kusunose, Hirotsugu Yamada, Takashi Todoroki, Susumu Nishio, Toshiyuki Niki, Koji Yamaguchi, Kunihiko Koshiba, Shusuke Yagi, Takashi Iwase, Takeshi Soeki, Tetsuzo Wakatsuki, Masashi Akaike, Tets

Journal:

Echocardiography

Year:

2009

Language:

english

File:

PDF, 221 KB

english, 2009

17

Japan Pharmaceutical Manufacturers Association (JPMA) Survey on Background Control Data of Developmental and Reproductive Toxicity Studies in Rats, Rabbits and Mice

Toshio NAKATSUKA, Masao HORIMOTO, Minako ITO, Yoshio MATSUBARA, Masashi AKAIKE, Fumio ARIYUKI

Journal:

Congenital Anomalies

Year:

1997

Language:

english

File:

PDF, 3.11 MB

english, 1997

18

Cardiac dysfunction in patients with chronic progressive external ophthalmoplegia

Masashi Akaike, Hisaomi Kawai, Kenji Yokoi, Makoto Kunishige, Hideki Mine, Yoshihiko Nishida, Shiro Saito

Journal:

Clinical Cardiology

Year:

1997

Language:

english

File:

PDF, 632 KB

english, 1997

19

Effects of percutaneous transvenous mitral commissurotomy on levels of plasma atrial natriuretic peptide during exercise

Fuminobu Ishikura, Seiki Nagata, Masashi Akaike, Jun Tamai, Kunio Miyatake

Journal:

The American Journal of Cardiology

Year:

1991

Language:

english

File:

PDF, 485 KB

english, 1991

20

Dual actions of nitric oxide inN-methyl-d-aspartate receptor-mediated neurotoxicity in cultured retinal neurons

Satoshi Kashii, Michiko Mandai, Masashi Kikuchi, Yoshihito Honda, Yutaka Tamura, Katsuyuki Kaneda, Akinori Akaike

Journal:

Year:

1996

Language:

english

File:

PDF, 1.19 MB

english, 1996

21

Hyperactivity and spatial maze learning impairment of adult rats with temporary neonatal hypothyroidism

Masashi Akaike, Nobumasa Kato, Hiroko Ohno, Takayoshi Kobayashi

Journal:

Neurotoxicology and Teratology

Year:

1991

Language:

english

File:

PDF, 594 KB

english, 1991

22

Effect of Low-Dose (1 mg/day) Pitavastatin on Left Ventricular Diastolic Function and Albuminuria in Patients With Hyperlipidemia

Shusuke Yagi, Masashi Akaike, Ken-Ichi Aihara, Takashi Iwase, Kazue Ishikawa, Sumiko Yoshida, Yuka Sumitomo-Ueda, Kenya Kusunose, Toshiyuki Niki, Koji Yamaguchi, Kunihiko Koshiba, Yoshio Taketani, Nor

Journal:

The American Journal of Cardiology

Year:

2011

Language:

english

File:

PDF, 782 KB

english, 2011

23

Reversible left ventricular dysfunction complicating eating disorder

Sumiko Shibuya-Tayoshi, Takahide Taniguchi, Chikako Moriya, Takaya Matsushita, Masashi Akaike, Shu-ichi Ueno, Tetsuro Ohmori

Journal:

General Hospital Psychiatry

Year:

2006

Language:

english

File:

PDF, 451 KB

english, 2006

24

A case of neurogenic myocardial stunning presenting transient left ventricular mid-portion ballooning simulating atypical takotsubo cardiomyopathy

Koji Yamaguchi, Tetsuzo Wakatsuki, Kenya Kusunose, Toshiyuki Niki, Kunihiko Koshiba, Hirotsugu Yamada, Takeshi Soeki, Masashi Akaike

Journal:

Journal of Cardiology

Year:

2008

Language:

english

File:

PDF, 1.32 MB

english, 2008

25

Changed preference for sweet taste in adulthood induced by perinatal exposure to bisphenol A—A probable link to overweight and obesity

Xiaobin Xu, Luei Tan, Toshiyuki Himi, Miyuki Sadamatsu, Shunsuke Tsutsumi, Masashi Akaike, Nobumasa Kato

Journal:

Neurotoxicology and Teratology

Year:

2011

Language:

english

File:

PDF, 559 KB

english, 2011

26

Potentiation by ethanol of GABA-induced current and facilitation of its desensitization in cultured rat cortical neurons

Shuji Tsujiyama, Akinori Akaike, Hisamitsu Ujihara, Masashi Sasa

Journal:

General Pharmacology: The Vascular System

Year:

1997

Language:

english

File:

PDF, 555 KB

english, 1997

27

Learning/Memory Impairments in Rat Offspring Prenatally Exposed to Phenytoin

Shunsuke Tsutsumi, Masashi Akaike, Hiroko Ohno, Nobumasa Kato

Journal:

Neurotoxicology and Teratology

Year:

1998

Language:

english

File:

PDF, 425 KB

english, 1998

28

High Cell-Density Culture System of Hepatocytes Entrapped in a Three-Dimensional Hollow Fiber Module with Collagen Gel

Kazuyoshi Takeshita, Haruaki Ishibashi, Masayuki Suzuki, Takumi Yamamoto, Toshihiro Akaike, Masashi Kodama

Journal:

Artificial Organs

Year:

1995

Language:

english

File:

PDF, 255 KB

english, 1995

29

Direct secretion from left atrium and pulmonary extraction of human atrial natriuretic peptide

Masashi Akaike, Fuminobu Ishikura, Seiki Nagata, Kohji Kimura, Kunio Miyatake

Journal:

American Heart Journal

Year:

1992

Language:

english

File:

PDF, 618 KB

english, 1992

30

Excitatory and inhibitory effects of dopamine on neuronal activity of the caudate nucleus neurons in vitro

Akinori Akaike, Yukihiro Ohno, Masashi Sasa, Shuji Takaori

Journal:

Year:

1987

Language:

english

File:

PDF, 948 KB

english, 1987

31

Dopamine-induced protection of striatal neurons against kainate receptor-mediated glutamate cytotoxicity in vitro

Taku Amano, Hisamitsu Ujihara, Hiroaki Matsubayashi, Masashi Sasa, Takeharu Yokota, Yutaka Tamura, Akinori Akaike

Journal:

Year:

1994

Language:

english

File:

PDF, 724 KB

english, 1994

32

PS-18-7 Homozygous adhalin gene mutations in adhalin deficient malignant limb-girdle muscular dystrophy and changes in hydrophobicity/ hydrophobicity in the adhalin molecule

Hisaomi Kawai, Masashi Akaike, Takenori Endo, Takayuki Tsuchihashi, Katsuhito Adachi, Toshio Inui, Setsuko Kashiwagi, Kazuo Miyoshi, Kiichiro Matsumura, Shiro Saito

Journal:

Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control

Year:

1995

Language:

english

File:

PDF, 127 KB

english, 1995

33

PS-18-4 Estimation of cardiac function by the plasma concentration of brain natriuretic peptide in patients with duchenne muscular dystrophy

Setsuko Kashiwagi, Masashi Akaike, Hisaomi Kawai, Katsuhito Adachi, Shiro Saito

Journal:

Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control

Year:

1995

Language:

english

File:

PDF, 128 KB

english, 1995

34

PS-49-1 Oxidative damage to skeletal muscle DNA from patients with mitochondrial encephalomyopathies

Takao Mitsui, Hisaomi Kawai, Masakazu Nagasawa, Makoto Kunishige, Masashi Akaike, Yuzo Kimura, Shiro Saito

Journal:

Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control

Year:

1995

Language:

english

File:

PDF, 119 KB

english, 1995

35

PS-49-2 Amounts of myoglobin and antioxidant enzymes in ragged-red fiber of patients with mitochondrial encephalomyopathy

Makoto Kunishige, Takao Mitsui, Masashi Akaike, Hisaomi Kawai, Shiro Saito

Journal:

Electroencephalography and Clinical Neurophysiology/Electromyography and Motor Control

Year:

1995

Language:

english

File:

PDF, 126 KB

english, 1995

36

Reprogramming of somatic cells induced by fusion of embryonic stem cells using hemagglutinating virus of Japan envelope (HVJ-E)

Xiao-shan Yue, Masako Fujishiro, Masashi Toyoda, Toshihiro Akaike, Yoshihiro Ito

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 625 KB

english, 2010

37

Synthetic prostacycline agonist, ONO-1301, ameliorates left ventricular dysfunction and cardiac fibrosis in cardiomyopathic hamsters

Yoichiro Hirata, Takeshi Soeki, Masashi Akaike, Yoshiki Sakai, Takashi Igarashi, Masataka Sata

Journal:

Biomedicine & Pharmacotherapy

Year:

2009

Language:

english

File:

PDF, 786 KB

english, 2009

38

Successful Autologous Peripheral Blood Stem Cell Transplantation for Primary Cardiac Amyloidosis Patients with Heart Failure: Three Cases Report

Takayuki Ise, Takashi Iwase, Kumiko Kagawa, Yuka Ueda, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masahiro Abe, Masashi Akaike, Masataka Sata

Journal:

Journal of Cardiac Failure

Year:

2011

Language:

english

File:

PDF, 151 KB

english, 2011

39

Comparison of chronic-stage histopathological findings among 3 coronary stents implanted in the same patient

Toshiyuki Niki, Tetsuzo Wakatsuki, Koji Yamaguchi, Kenya Kusunose, Kunihiko Koshiba, Shusuke Yagi, Yoshio Taketani, Takashi Iwase, Noriko Tomita, Hirotsugu Yamada, Takeshi Soeki, Masashi Akaike, Masat

Journal:

International Journal of Cardiology

Year:

2011

Language:

english

File:

PDF, 459 KB

english, 2011

40

Local persistent hypercoagulability after sirolimus-eluting stent implantation in patients with stable angina

Koji Yamaguchi, Tetsuzo Wakatsuki, Toshiyuki Niki, Kenya Kusunose, Kunihiko Koshiba, Shusuke Yagi, Yoshio Taketani, Takashi Iwase, Noriko Tomita, Hirotsugu Yamada, Takeshi Soeki, Masashi Akaike, Masat

Journal:

International Journal of Cardiology

Year:

2011

Language:

english

File:

PDF, 901 KB

english, 2011

41

Bosentan improves systemic sclerosis-related peripheral circulation insufficiency

Shusuke Yagi, Masashi Akaike, Ken-ichi Aihara, Takashi Iwase, Yuka Sumitomo-Ueda, Sumiko Yoshida, Toshio Matsumoto, Masataka Sata

Journal:

International Journal of Cardiology

Year:

2011

Language:

english

File:

PDF, 991 KB

english, 2011

42

Acute hemodynamic effects of adaptive servo ventilation in patients with pulmonary hypertension

Shusuke Yagi, Masashi Akaike, Takashi Iwase, Kenya Kusunose, Toshiyuki Niki, Koji Yamaguchi, Kunihiko Koshiba, Yoshio Taketani, Noriko Tomita, Hirotsugu Yamada, Takeshi Soeki, Tetsuzo Wakatsuki, Masat

Journal:

International Journal of Cardiology

Year:

2011

Language:

english

File:

PDF, 123 KB

english, 2011

43

Cardiac dysfunction with Becker muscular dystrophy

Miho Saito, Hisaomi Kawai, Masashi Akaike, Katsuhito Adachi, Yoshihito Nishida, Shiro Saito

Journal:

American Heart Journal

Year:

1996

Language:

english

File:

PDF, 596 KB

english, 1996

44

Vascular smooth muscle cell proliferation is dependent upon upregulation of mitochondrial transcription factor A (mtTFA) expression in injured rat carotid artery

Tomonori Yoshida, Hiroyuki Azuma, Ken-ichi Aihara, Mitsunori Fujimura, Masashi Akaike, Takao Mitsui, Toshio Matsumoto

Journal:

Atherosclerosis

Year:

2005

Language:

english

File:

PDF, 583 KB

english, 2005

45

Aspirin inhibits thrombin action on endothelial cells via up-regulation of aminopeptidase N/CD13 expression

Midori Kato, Hiroyuki Azuma, Masashi Akaike, Takahiko Iuchi, Ken-ichi Aihara, Yasumasa Ikeda, Mitsunori Fujimura, Tomonori Yoshida, Hiroshi Yamaguchi, Shunji Hashizume, Toshio Matsumoto

Journal:

Atherosclerosis

Year:

2005

Language:

english

File:

PDF, 165 KB

english, 2005

46

Dopamine D1/D2 Receptor Interaction

Masashi Sasa, Akinori Akaike, Yukihiro Ohno, Mitsuyoshi Hara, Shuji Takaori

Journal:

Psychiatry and Clinical Neurosciences

Year:

1991

Language:

english

File:

PDF, 183 KB

english, 1991

47

Trimethyltin (TMT)-Treated Rats with Specific Hippocampal Lesion as a Possible Model of Endocrine Abnormality in Depression

Miyuki Sadamatsu, Akira Masui, Hirohiko Kanai, Nobumasa Kato, Masashi Akaike, Syunsuke Tsutsumi

Journal:

Psychiatry and Clinical Neurosciences

Year:

1992

Language:

english

File:

PDF, 93 KB

english, 1992

48

The Susceptibility of Pentylenetetrazole-Induced Seizure in Rats with Hippocampal Lesion Induced by Trimethyltin

Nobuya Ishida, Hirohiko Kanai, Nobumasa Kato, Masashi Akaike

Journal:

Psychiatry and Clinical Neurosciences

Year:

1993

Language:

english

File:

PDF, 167 KB

english, 1993

49

Inhibition from ventral tegmental area of nucleus accumbens neurons in the rat

Akinori Akaike, Masashi Sasa, Shuji Takaori

Journal:

Year:

1981

Language:

english

File:

PDF, 727 KB

english, 1981

50

Oxidative damage to skeletal muscle DNA from patients with mitochondrial encephalomyopathies

Takao Mitsui, Hisaomi Kawai, Masakazu Nagasawa, Makoto Kunishige, Masashi Akaike, Yuzo Kimura, Shiro Saito

Journal:

Journal of the Neurological Sciences

Year:

1996

Language:

english

File:

PDF, 1.80 MB

english, 1996